Dimethylformamide → Acetyl chloride, (4-cyanophenoxy)-

HRID 520833Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 520833
[C:1]([C:3]1[CH:13]=[CH:12][C:6]([O:7][CH2:8][C:9](O)=[O:10])=[CH:5][CH:4]=1)#[N:2].C(Cl)(=O)C([Cl:17])=O.CN(C)C=O>ClCCl>[C:1]([C:3]1[CH:13]=[CH:12][C:6]([O:7][CH2:8][C:9]([Cl:17])=[O:10])=[CH:5][CH:4]=1)#[N:2]

Komponenten

5

Edukt 3

HCID 6228DimethylformamideHCID 65578Oxalyl chlorideHCID 7360972-(4-Cyanophenoxy)acetic acid

Produkt 1

HCID 12207748Acetyl chloride, (4-cyanophenoxy)-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

To a suspension of commercially available 2-(4-cyanophenoxy)acetic acid (4.0 g, 22.6 mmol) in dichloromethane (80 mL) was added oxalyl chloride (2.17 mL, 24.8 mmol). To this mixture was added N,N-dimethylformamide (30 μL) dropwise and the mixture was stirred for 2 hours during which cessation of evolution of gas was observed. The resulting solution was diluted with dichloromethane (50 mL) and the solvent was removed under reduced pressure to provide the title compound as an oil which became a solid upon storing in the refrigerator.

Aufarbeitung

  1. customthe solvent was removed under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-00020fe290904569b680f086c2c5b012
Quelldatensatz
uspto-grants-2016_05
Patentnummer
US09328095B2

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