tert-butyl ((2S,3S)-3-((R)-hex-5-en-2-yloxy)-1-((2S,4R)-4-hydroxy-2-(((1R,2S)-1-(((1-methylcyclopropyl)sulfonyl)carbamoyl)-2-vinylcyclopropyl)carbamoyl)pyrrolidin-1-yl)-1-oxopentan-2-yl)carbamate → tert-butyl ((2R,6S,7S,9R,13aS,14aR,16aS,Z)-7-ethyl-2-hydroxy-9-methyl-14a-(((1-methylcyclopropyl)sulfonyl)carbamoyl)-5,16-dioxo-2,3,5,6,7,9,10,11,13a,14,14a,15,16,16a-tetradecahydro-1H-cyclopropa[i]pyrrolo[1,2-e][1,5,8]oxadiazacyclopentadecin-6-yl)carbamate

Reaktionsgleichung

[CH3:1][C@@H:2]([O:7][C@@H:8]([CH2:44][CH3:45])[C@H:9]([NH:36][C:37](=[O:43])[O:38][C:39]([CH3:42])([CH3:41])[CH3:40])[C:10]([N:12]1[CH2:16][C@H:15]([OH:17])[CH2:14][C@H:13]1[C:18](=[O:35])[NH:19][C@:20]1([C:25](=[O:34])[NH:26][S:27]([C:30]2([CH3:33])[CH2:32][CH2:31]2)(=[O:29])=[O:28])[CH2:22][C@H:21]1C=C)=[O:11])[CH2:3][CH2:4][CH:5]=[CH2:6]>CC1C=C(C)C=C(C)C=1N1CCN(C2C(C)=CC(C)=CC=2C)C1=[Ru](Cl)(Cl)=CC1C=CC=CC=1OC(C)C.ClCCCl>[CH2:44]([C@H:8]1[C@H:9]([NH:36][C:37](=[O:43])[O:38][C:39]([CH3:40])([CH3:42])[CH3:41])[C:10](=[O:11])[N:12]2[CH2:16][C@H:15]([OH:17])[CH2:14][C@H:13]2[C:18](=[O:35])[NH:19][C@:20]2([C:25](=[O:34])[NH:26][S:27]([C:30]3([CH3:33])[CH2:31][CH2:32]3)(=[O:29])=[O:28])[CH2:21][C@H:22]2[CH:6]=[CH:5][CH2:4][CH2:3][C@@H:2]([CH3:1])[O:7]1)[CH3:45]