Sodium Iodide → HCID 86717343, Verbindung

To a solution of 2-chloro-2-(4-isopropyl-2-methoxyphenyl)-1H-inden-1,3(2H)-dione (0.10 g, 0.3 mmol) in acetone (5 ml) were added with sodium iodide (54 mg, 0.36 mmol) and sodium azide (50 mg, 0.76 mmol) and distilled water (1 ml), followed by stirring at 80° C. for 6 hrs. The reaction mixture was added water, and extracted diethyl ether, and washed with water and brine in that order. The washed organic layer was concentrated to afford the title compound (100 g, 98%).

1. distillationdistilled water (1 ml)
2. additionThe reaction mixture was added water
3. extractionextracted diethyl ether
4. washwashed with water and brine in that order
5. concentrationThe washed organic layer was concentrated

ORD-Eintrag

ord-6816e6c7cc9f48f6b9e1752cf723252c

Quelldatensatz

uspto-grants-2016_05

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US09346749B2