Z-3-(1,3-dioxan-2-yl)-1-(2-pyridyl)-1-propene → 1-(1,3-Dioxan-2-yl)-3-(2-pyridyl)propane

HRID 53565

Reaktionsgleichung

Reaktionsgleichung von HRID 53565
[O:1]1[CH2:6][CH2:5][CH2:4][O:3][CH:2]1[CH2:7]/[CH:8]=[CH:9]\[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][N:11]=1>[Pd]>[O:1]1[CH2:6][CH2:5][CH2:4][O:3][CH:2]1[CH2:7][CH2:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][N:11]=1

Komponenten

3

Edukt 1

HCID 70113689Z-3-(1,3-dioxan-2-yl)-1-(2-pyridyl)-1-propene

Produkt 1

HCID 196941391-(1,3-Dioxan-2-yl)-3-(2-pyridyl)propaneAusbeute 92,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

Through a suspension of 800 mg (4.2 mmol) of olefin 149 and 100 mg of 10% palladium on carbon was bubbled a steady stream of hydrogen gas for a period of 10 min. The reaction mixture was then filtered through celite and concentrated to give 805 mg of the acetal 150 as a colorless oil. 1H NMR consistent with structure.

Aufarbeitung

  1. customwas bubbled a steady stream of hydrogen gas for a period of 10 min
  2. filtrationThe reaction mixture was then filtered through celite and
  3. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-bf8ddce61e554c87a399e80c329d67fa
Quelldatensatz
uspto-grants-1997_04
Patentnummer
US05620971

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