2-(3-Nitrophenoxy)tetrahydro-2H-pyran → HCID 12046288, Verbindung
Reaktionsgleichung
[N+:1]([C:4]1[CH:5]=[C:6]([CH:14]=[CH:15][CH:16]=1)[O:7][CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][O:9]1)([O-])=O>CO.[Pd]>[O:9]1[CH2:10][CH2:11][CH2:12][CH2:13][CH:8]1[O:7][C:6]1[CH:5]=[C:4]([CH:16]=[CH:15][CH:14]=1)[NH2:1]Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Reaktionsbedingungen
- Temperatur
- 25 °C
Versuchsvorschrift
A solution of 2-(3-nitrophenoxy)tetrahydro-2H-pyran (1.0 g, 4.5 mmol) in methanol (13 mL) was degassed with nitrogen (3×) and treated with 10% Pd/C (wet Degussa type) (12 mg). The reaction mixture was degassed and stirred under an atmosphere of hydrogen at 25° C. for 2 h. The reaction mixture was filtered to give the desired product (0.87 g, quantitative) as a tan oil. LCMS for C11H16NO2 (M+H)+: m/z=194.0.