Magnesium Sulfate Heptahydrate → L-Aspartic Acid

HRID 542164

Reaktionsgleichung

Reaktionsgleichung von HRID 542164
[C:1]([O-:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([O-:6])=[O:5].[NH4+:9].[NH4+].P([O-])(O)(O)=O.[K+].O.O.O.O.O.O.O.S([O-])([O-])(=O)=O.[Mg+2]>>[NH2:9][C@H:2]([C:1]([OH:8])=[O:7])[CH2:3][C:4]([OH:6])=[O:5]

Komponenten

4

Edukt 3

HCID 24843Magnesium Sulfate HeptahydrateHCID 516951Monobasic potassium phosphateHCID 9793847Ammonium fumarate

Produkt 1

HCID 5960L-Aspartic Acid

Versuchsvorschrift

Serratia marcescens TA5002 was inoculated in a medium (500 ml, pH 7.0) containing ammonium fumarate (3%), potassium dihydrogen phosphate (0.2%), magnesium sulfate heptahydrate (0.05%), corn steep liquor (4%) and yeast extract (2%) and cultivated at 30° C. for 18 hours. The resulting culture was adjusted to pH 8.5 with aqueous ammonia and added thereto ammonium fumarate (65 g) and Triton X-100 (500 mg). The mixture was allowed to react at 37° C. for 5 hours. Then, the reaction mixture was filtered, concentrated and adjusted to pH 2.8 to precipitate crude crystals of L-aspartic acid. The crude crystals were filtered off and recrystallized from water to give L-aspartic acid (46.5 g).

Aufarbeitung

  1. extractionextract (2%)
  2. additionadded
  3. customto react at 37° C. for 5 hours
  4. filtrationThen, the reaction mixture was filtered
  5. concentrationconcentrated
  6. customto precipitate crude crystals of L-aspartic acid
  7. filtrationThe crude crystals were filtered off
  8. customrecrystallized from water

Quellen und Nachweise

ORD-Eintrag
ord-59fced78df824e9caccefbeec0052388
Quelldatensatz
uspto-grants-1987_04
Patentnummer
US04656136

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