Grundinformationen
- Standard-SMILES
O.O.O.O.O.O.O.O=S(=O)([O-])[O-].[Mg+2]- InChIKey
WRUGWIBCXHJTDG-UHFFFAOYSA-L- Summenformel
- Mg.S.O4.7H2O
- Durchschnittliche Molmasse
- 246,48 g/mol
- Monoisotopische Masse
- 246,01072397
Überblick
Magnesium sulfate heptahydrate is a hydrate that is the heptahydrate form of magnesium sulfate. It has a role as a laxative and a cathartic. It is a magnesium salt and a hydrate. It contains a magnesium sulfate.
Namen und Bezeichner
- Bevorzugter Name
- Magnesium Sulfate Heptahydrate
- IUPAC
- magnesium;sulfate;heptahydrate
- Englischer Name
- Magnesium sulfate heptahydrate
- Summenformel
- Mg.O4S.7H2O
- Molmasse
- 246.47
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
10034-99-8、14457-55-7- PubChem CID
- 24843
- DTXSID
DTXSID5040544- ChEBI
CHEBI:31795- UNII
- SK47B8698T
- EC Number
- 600-073-4、913-387-4
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 95,6 Ų
- H-Brücken-Donoren
- 7
- H-Brücken-Akzeptoren
- 11
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 13
- Formalladung
- 0
- Komplexität
- 62,2
Experimentelle und physikochemische Eigenschaften
Physikochemische Eigenschaften
- Schmelzpunkt
- 1124 °C · 1124°C
- Dichte
- 2.66 · 2.66
- Dampfdichte
- 0.01 · <0.01 (vs air)
- Dampfdruck
- 0.1 mm · <0.1 mm Hg ( 20 °C)
- Brechungsindex
- 1.433 · 1.433
- storage temp.
- 5 °C · Store at +5°C to +30°C.
- Löslichkeit
- 2 O: · H2O: 1 M at 20 °C, clear, colorless
- Aggregatzustand
- Solid
- Wichte
- 1.68 · 1.68
- Farbe
- White
- PH
- 5 · 5.0-8.0 (25℃, 50mg/mL in H2O)
- Geruch (Odor)
- Odorless
- Wasserlöslichkeit
- Soluble in in water and acid. Slightly soluble in alcohol and glycerol.
- Merck
- 14 · 14,5691
- Dielectric constant
- 8.2 · 8.2(Ambient)
- Stabilität
- Stable. Non-flammable. May slowly deteriorate in contact with air.
- Kosmetik-Inhaltsstoffe Funktionen
- BULKING
- InChI
- 1S/Mg.H2O4S.7H2O/c;1-5(2,3)4;;;;;;;/h;(H2,1,2,3,4);7*1H2/q+2;;;;;;;;/p-2
- InChIKey
- WRUGWIBCXHJTDG-UHFFFAOYSA-L
- SMILES
- O.O.O.O.O.O.O.[Mg++].[O-]S([O-])(=O)=O
- LogP
- -1.031 · -1.031 (est)
- CAS Datenbank
- 10034 · 10034-99-8(CAS DataBase Reference)
- NIST chemische Informationen
- magnesium sulfate heptahydrate(10034-99-8)
- EPA chemische Informationen
- Magnesium sulfate heptahydrate (10034-99-8)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 100% (424 of 424) of all reports.
Not Classified
Aggregated GHS information provided per 424 reports by companies from 2 notifications to the ECHA C&L Inventory.
This chemical does not meet GHS hazard criteria for 100% (2 of 2) of all reports.
Not Classified
Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory.
Gefahrenhinweise
Regulatory Information
Chemical: Sulfuric acid, magnesium salt, heptahydrate
Sulfuric acid magnesium salt (1:1), heptahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sulfuric acid magnesium salt (1:1), heptahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Sulfuric acid magnesium salt (1:1), heptahydrate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories
Not Classified
Not Classified
Sicherheit und Schutzausrüstung
Protective Action Criteria (PAC)
1.2 [mg/m3]
13 [mg/m3]
81 [mg/m3]
Sicherheitsdaten
- wgk
- 1
- tsca
- Yes
- hs_code
- 28332100
- RTECS-Nr.
- OM4508000
- risk_code
- 36/37/38
- Toxizität
- man,TDLo,oral,183mg/kg/4H-I (183mg/kg),GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA",Journal of Toxicology, Clinical Toxicology. Vol. 20, Pg. 107, 1983.
- hazard_code
- Xi
- safety_code
- 24/25-36-26
- Speicherklasse
- 13 - Non Combustible Solids
Chemie und Industrie
Pharmakologische Informationen
FDA Pharmacological Classification
50% MAGNESIUM SULFATE
Increased Large Intestinal Motility [PE]; Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]; Inhibition Small Intestine Fluid/Electrolyte Absorption [PE]; Magnesium Ion Exchange Activity [MoA]; Osmotic Laxative [EPC]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]; Calculi Dissolution Agent [EPC]
EPSOM SALT
Calculi Dissolution Agent [EPC]; Osmotic Activity [MoA]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Laxative [EPC]; Magnesium Ion Exchange Activity [MoA]; Inhibition Small Intestine Fluid/Electrolyte Absorption [PE]; Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]; Increased Large Intestinal Motility [PE]
MAGNESIA SULPHURICA
Calculi Dissolution Agent [EPC]; Osmotic Activity [MoA]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Laxative [EPC]; Magnesium Ion Exchange Activity [MoA]; Inhibition Small Intestine Fluid/Electrolyte Absorption [PE]; Stimulation Large Intestine Fluid/Electrolyte Secretion [PE]; Increased Large Intestinal Motility [PE]
MeSH Pharmacological Classification
Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
Agents capable of inducing a total or partial loss of sensation, especially tactile sensation and pain. They may act to induce general ANESTHESIA, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site.
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Drugs used to prevent SEIZURES or reduce their severity.
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete.
Verwendung und Herstellung
Use Classification
EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives
Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern
Anwendungen
BeschreibungIn addition to its use in foods as a flavor enhancer, nutrient supplement and processing aid, magnesium sulfate (as Epsom salt) is employed in over-the-counter preparations as a laxative. As a legend (prescription drug) it has been used as an anticonvulsant and electrolyte replenisher.
VerwendenMagnesium sulfate heptahydrate has been used:as a component in Kreb′s Ringer bufferas a component in minimal medium to culture Ralstonia solanacearumin the preparation of maceration solution for Lamb′s lettuce cell isolation and isotonic glucose buffer
Vor- und nachgelagerte Produkte
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Ergänzende Hinweise
DefinitionEpsomite: a mineral form of magnesiumsulphate heptahydrate,MgSO4.7H2O.
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