2,3-Quinolinedicarboxylic acidtrihydrate → Furo[3,4-b]quinoline-1,3-dione

HRID 542273

Reaktionsgleichung

O.O.O.[N:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[C:6]([C:14]([OH:16])=O)[C:5]=1[C:17]([OH:19])=[O:18]>C(OC(=O)C)(=O)C>[N:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[C:6]2[C:14]([O:19][C:17](=[O:18])[C:5]=12)=[O:16]

Komponenten

Reaktionsbedingungen

Temperatur: 85 °C

Versuchsvorschrift

A mixture of 2,3-quinolinedicarboxylic acid-trihydrate (0.141 mol) in acetic anhydride (125 mL) is heated at 85° C. for one-half hour and then at 100° C. for one hour. The reaction mixture is then cooled to room temperature, filtered and the solids washed with ethyl ether to afford the desired 2,3-quinolinedicarboxylic anhydride, mp 225°-228° C.

Aufarbeitung

temperatureThe reaction mixture is then cooled to room temperature
filtrationfiltered
washthe solids washed with ethyl ether

Quellen und Nachweise

ORD-Eintrag: ord-e3894643fa59463a8c1c38b778537b7e
Quelldatensatz: uspto-grants-1987_04
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US04656283

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