Acetonitrile → Debrisoquine

HRID 542286Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 542286
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][NH:2]1.N[N:12]=[CH:13]S(O)(=O)=O.C(#[N:20])C>>[CH:7]1[CH:8]=[CH:9][C:10]2[CH2:1][N:2]([C:13]([NH2:12])=[NH:20])[CH2:3][CH2:4][C:5]=2[CH:6]=1

Komponenten

4

Edukt 3

HCID 6342AcetonitrileHCID 70461,2,3,4-TetrahydroisoquinolineHCID 3013981Aminoiminomethane-sulphonic acid

Produkt 1

HCID 2966Debrisoquine

Versuchsvorschrift

Tetrahydroisoquinoline (0.013 m) is treated with aminoiminomethanesulfonic acid (0.01 m) at ambient temperature. After completion of the reaction, it is diluted with acetonitrile, cooled and the solid product is collected by filtration.

Aufarbeitung

  1. customAfter completion of the reaction, it
  2. temperaturecooled
  3. filtrationthe solid product is collected by filtration

Quellen und Nachweise

ORD-Eintrag
ord-0cd5d279cd8c49429e14cc8a53a6b393
Quelldatensatz
uspto-grants-1987_04
Patentnummer
US04656291

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