L-(-)-Sorbose → alpha-L-Sorbofuranose, 2,3:4,6-bis-o-(1-methylethylidene)-

HRID 542921

Reaktionsgleichung

Reaktionsgleichung von HRID 542921
[OH:1][CH2:2][C:3]([C@H:5]([C@@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])=[O:4].[Sb](F)(F)(F)(F)F>CC(C)=O>[CH3:2][C:3]1([CH3:5])[O:6][CH:5]2[CH:7]3[O:8][C:9]([CH3:11])([CH3:7])[O:10][C:9]3([CH2:11][OH:12])[O:4][CH:3]2[CH2:2][O:1]1

Komponenten

4

Edukt 2

HCID 6904L-(-)-SorboseHCID 24557Antimony pentafluoride

Produkt 1

HCID 140270alpha-L-Sorbofuranose, 2,3:4,6-bis-o-(1-methylethylidene)-Ausbeute 164,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Reaktionsbedingungen

Temperatur
60 °C

Versuchsvorschrift

To 200 ml of acetone were added 10.0 g of L-sorbose and 65.0 mg of antimony pentafluoride, and the mixture was refluxed with stirring in a water bath of 60° C. for 6 hours. During this reaction, the refluxing solvent was dried with 20 g of Molecular Sieves 3A interposed between the reaction vessel and the condenser. The quantitative analysis of the reaction solution according to the same procedure as described in Example 14 showed that there was obtained 11.89 g (82.3%) of 2,3:4,6-di-O-isopropylidene-α-L-sorbofuranose.

Aufarbeitung

  1. temperaturethe mixture was refluxed
  2. customDuring this reaction
  3. dry with materialthe refluxing solvent was dried with 20 g of Molecular Sieves 3A

Quellen und Nachweise

ORD-Eintrag
ord-a73e3fa2ba72475993941e866dc825e4
Quelldatensatz
uspto-grants-1987_04
Patentnummer
US04659809

Verknüpfte Notizen

Wird geladen…