Ammonium Hydroxide → 2-{2-[(2-hydroxyethyl)amino]-1H-benzimidazol-1-yl}-1-phenylethanone

HRID 54690Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 54690
[OH-].[NH4+].Br.Br.[OH:5][CH2:6][CH2:7][NH:8][C:9]1[N:13]([CH2:14][C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:16])[C:12]2[CH:23]=[CH:24][CH:25]=[CH:26][C:11]=2[N:10]=1>>[OH:5][CH2:6][CH2:7][NH:8][C:9]1[N:13]([CH2:14][C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:16])[C:12]2[CH:23]=[CH:24][CH:25]=[CH:26][C:11]=2[N:10]=1

Komponenten

3

Edukt 2

HCID 14923Ammonium HydroxideHCID 190408002-(2-Hydroxyethylamino)-1-phenacylbenzimidazole dihydrobromide

Produkt 1

HCID 28501002-{2-[(2-hydroxyethyl)amino]-1H-benzimidazol-1-yl}-1-phenylethanone

Versuchsvorschrift

Add 22% ammonium hydroxide to 75 ml of a hot solution of the dihydrobromide obtained in Step A in 95° alcohol until a pH of approximately 10 is obtained. The title compound precipitates and is filtered, washed with water and dried.

Aufarbeitung

  1. customis obtained
  2. customThe title compound precipitates
  3. filtrationis filtered
  4. washwashed with water
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-31389e86c4f54555a7926b88794f66ba
Quelldatensatz
uspto-grants-1997_04
Patentnummer
US05623073

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