Hydrazine hydrate (1:1) → Pyridazine-4-carbohydrazide
Reaktionsgleichung
[N:1]1[CH:6]=[CH:5][C:4]([C:7]([O:9]C)=O)=[CH:3][N:2]=1.O.[NH2:12][NH2:13]>CO>[N:1]1[CH:6]=[CH:5][C:4]([C:7]([NH:12][NH2:13])=[O:9])=[CH:3][N:2]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of methyl 4-pyridazinecarboxylate (400 mg, 2.9 mmol) in MeOH (5 ml) was added hydrazine monohydrate (23 mmol). The solution was heated to reflux for 12 h. Volatiles were evaporated in vacuo to give 395 mg of the title compound as a yellow pale foam, which was used without further purification.
Aufarbeitung
- temperatureThe solution was heated
- temperatureto reflux for 12 h
- customVolatiles were evaporated in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-f2c703a19ce148b9a847c42d4312d49e
- Quelldatensatz
- uspto-grants-2011_05
- Patentnummer
- US07947683B2
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