Butylate → 7-Methoxy-1-vinylnaphthalene

HRID 551776

Reaktionsgleichung

Reaktionsgleichung von HRID 551776
CS(O[CH2:6][CH2:7][C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[C:15]([O:18][CH3:19])[CH:16]=2)[CH:11]=[CH:10][CH:9]=1)(=O)=O.[K].CCSC(N(CC(C)C)CC(C)C)=O>O1CCCC1.O>[CH3:19][O:18][C:15]1[CH:16]=[C:17]2[C:12]([CH:11]=[CH:10][CH:9]=[C:8]2[CH:7]=[CH2:6])=[CH:13][CH:14]=1

Komponenten

6

Edukt 3

HCID 16181ButylateHCID 5462222PotassiumHCID 190859902-(7-Methoxynaphthalen-1-yl)ethyl methanesulfonate

Produkt 1

HCID 445416687-Methoxy-1-vinylnaphthalene

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

The compound obtained in Step A (21.4 mmol) is dissolved in 120 ml of tetrahydrofuran, and potassium tent-butylate (64.2 mmol) is added in small portions. After stirring for 30 minutes at ambient temperature, the reaction mixture is evaporated to dryness. The residue obtained is taken up in 150 ml of water and the aqueous phase is extracted twice with 60 ml of diethyl ether. The organic phase is washed with water, dried over magnesium sulphate, decolourised on vegetable carbon and evaporated. The residue obtained is purified on silica gel (eluant: petroleum ether) to yield the title product in the form of a yellow oil.

Aufarbeitung

  1. customthe reaction mixture is evaporated to dryness
  2. customThe residue obtained
  3. extractionthe aqueous phase is extracted twice with 60 ml of diethyl ether
  4. washThe organic phase is washed with water
  5. dry with materialdried over magnesium sulphate
  6. customevaporated
  7. customThe residue obtained
  8. customis purified on silica gel (eluant: petroleum ether)

Quellen und Nachweise

ORD-Eintrag
ord-c307d8c7baac4019b1c29cce6b41bdff
Quelldatensatz
uspto-grants-2011_05
Patentnummer
US07947852B2

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