Ethylamine → [2-(5-Bromo-2-methoxy-pyridin-3-yl)-5-trifluoromethyl-benzyl]-ethyl-amine
Reaktionsgleichung
[Br:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][C:11]=2[CH:12]=O)[C:5]([O:8][CH3:9])=[N:6][CH:7]=1.[CH2:22]([NH2:24])[CH3:23]>>[Br:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][C:11]=2[CH2:12][NH:24][CH2:22][CH3:23])[C:5]([O:8][CH3:9])=[N:6][CH:7]=1Komponenten
3
Versuchsvorschrift
2-(5-Bromo-2-methoxy-pyridin-3-yl)-5-trifluoromethyl-benzaldehyde and ethylamine (2M in THF) as described in Example 3, Step 3 to provide [2-(5-bromo-2-methoxy-pyridin-3-yl)-5-trifluoromethyl-benzyl]-ethyl-amine.
Quellen und Nachweise
- ORD-Eintrag
- ord-d07eb64787db4410a54f68ea04ddf9bd
- Quelldatensatz
- uspto-grants-2011_11