Thionyl Chloride → 5-Methoxycarbonyl-2-thiophenecarboxylic acid hydrazide
Reaktionsgleichung
[CH3:1][O:2][C:3]([C:5]1[S:9][C:8]([C:10]([OH:12])=O)=[CH:7][CH:6]=1)=[O:4].S(Cl)(Cl)=O.O.[NH2:18][NH2:19]>>[CH3:1][O:2][C:3]([C:5]1[S:9][C:8]([C:10]([NH:18][NH2:19])=[O:12])=[CH:7][CH:6]=1)=[O:4]Komponenten
4
Versuchsvorschrift
The known procedure disclosed in the literature (J. Heterocyclic Chem., 28, 17, (1991).) was followed using 5-methoxycarbonyl-2-thiophenecarboxylic acid, thionyl chloride and hydrazine monohydrate to give 144 mg of a white solid (yield 72%).
Quellen und Nachweise
- ORD-Eintrag
- ord-bf6dfab621cf4be0b5b517f3fe18f364
- Quelldatensatz
- uspto-grants-2011_11
- Patentnummer
- US08053453B2
Notizen zur Reaktion
Wird geladen…