Potassium Iodide → 2,3-Epoxypropoxy Carbazole

Beteiligte Stoffe

Reaktionsschritte

100 g (0.55 moles) of 4-hydroxy carbazole is dissolved in 600 ml of acetone. To that 188 g (1.36 moles) potassium carbonate, 2.0 g potassium iodide and 0.5 g sodium dithionate are added under nitrogen. The reaction mass is refluxed for 1.0 hr, cooled to room temperature followed by the addition of 150 g (1.62 moles) of epichlorohydrin through a dropping funnel over 40-45 min at room temp. The reaction mass is further refluxed for 32 hrs and then cooled to room temp and filtered. The above filtrate is evaporated followed by recrystallisation of the crude product from methanol.

Herkunft & Nachweise