Nitrogen → 2-(3-Fluorophenoxy)-2-methylpropanoyl chloride

HRID 56276

Reaktionsgleichung

Reaktionsgleichung von HRID 56276
[F:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][CH:14]=1)[O:5][C:6]([CH3:11])([CH3:10])[C:7](O)=[O:8].[Cl:15]SCl.N#N>>[F:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][CH:14]=1)[O:5][C:6]([CH3:11])([CH3:10])[C:7]([Cl:15])=[O:8]

Komponenten

4

Edukt 3

HCID 947NitrogenHCID 25353Sulfur dichlorideHCID 222707202-(3-fluorophenoxy)-2-methylPropanoic acid

Produkt 1

HCID 821138502-(3-Fluorophenoxy)-2-methylpropanoyl chloride

Versuchsvorschrift

To 2-(3-fluorophenoxy)-2-methylpropanoic acid (1.70 g, 8.58 mmol) was added dichlorosulfane (15 mL) dropwise under N2 and the mixture was refluxed for 3 h. The mixture was cooled to rt and concentrated in vacuo to give the title compound as yellow oil, which was used for next step without further purification.

Aufarbeitung

  1. temperaturethe mixture was refluxed for 3 h
  2. concentrationconcentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-9e3a5970c34243519043534d48bb17a0
Quelldatensatz
uspto-grants-2016_09
Patentnummer
US09434695B2

Verknüpfte Notizen

Wird geladen…