Ethanol → Ethyl 3-bromo-4-methoxyphenylacetate

HRID 563594

Reaktionsgleichung

Reaktionsgleichung von HRID 563594
[Br:1][C:2]1[CH:3]=[C:4]([CH2:10][C:11]([OH:13])=[O:12])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[CH3:14][CH2:15]O>S(=O)(=O)(O)O>[CH2:14]([O:12][C:11](=[O:13])[CH2:10][C:4]1[CH:5]=[CH:6][C:7]([O:8][CH3:9])=[C:2]([Br:1])[CH:3]=1)[CH3:15]

Komponenten

4

Edukt 2

HCID 702EthanolHCID 1366153-Bromo-4-methoxyphenylacetic acid

Produkt 1

HCID 57419861Ethyl 3-bromo-4-methoxyphenylacetate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1118Sulfuric AcidLösungsmittel

Versuchsvorschrift

A solution of 3-bromo-4-methoxyphenylacetic acid (3.0 g, 12.2 mmol) in EtOH and sulfuric acid was stirred at 100° C. for 2 hours. The mixture was concentrated and partitioned between EtOAc and H2O, and the organic layer was separated to give the title compound.

Aufarbeitung

  1. concentrationThe mixture was concentrated
  2. custompartitioned between EtOAc and H2O
  3. customthe organic layer was separated

Quellen und Nachweise

ORD-Eintrag
ord-e3d6e9063a61482c9b1a0e69f21c57b7
Quelldatensatz
uspto-grants-2011_11
Patentnummer
US08067445B2

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