2-Amino-3,5-dinitropyridine → Pyridine-2,3,5-triamine

HRID 564001Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 564001
[NH2:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][C:5]([N+:11]([O-])=O)=[CH:4][N:3]=1>CO.C1COCC1.[Pd]>[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][C:5]([NH2:11])=[CH:4][N:3]=1

Komponenten

5

Edukt 1

HCID 5043402-Amino-3,5-dinitropyridine

Produkt 1

HCID 14626209Pyridine-2,3,5-triamineAusbeute 98,2 %

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittelHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

5 g 2-Amino-3,5-dinitropyridine in a mixture of 66 ml methanol and 33 ml THF were hydrogenated over 800 mg 10% palladium on charcoal at room temperature and atmospheric pressure. After the calculated amount of hydrogen was consumed, the catalyst was filtered off and the filtrate was concentrated under vacuum yielding 3.31 g of the crude product which was used for the next step without further purification.

Aufarbeitung

  1. customAfter the calculated amount of hydrogen was consumed
  2. filtrationthe catalyst was filtered off
  3. concentrationthe filtrate was concentrated under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-6e29d33d1009406391acf6a39d00ad7a
Quelldatensatz
uspto-grants-2011_11
Patentnummer
US08067599B2

Notizen zur Reaktion

Wird geladen…