1-Dodecanethiol → 1,3-Bis(dodecylsulfanyl)propan-2-ol

HRID 567186Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 567186
[CH2:1]([SH:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[Na].[CH2:15]([CH:17]1[O:19][CH2:18]1)Br>C(O)C.CCOCC>[CH2:1]([S:13][CH2:15][CH:17]([OH:19])[CH2:18][S:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Komponenten

6

Edukt 3

HCID 81951-DodecanethiolHCID 18430EpibromohydrinHCID 5360545Sodium

Produkt 1

HCID 158395031,3-Bis(dodecylsulfanyl)propan-2-ol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

26.6 ml Dodecanethiol was added to an ethylate solution of 2.6 g sodium in 100 ml ethanol and the solution was stirred for 1 hour at room temperature. Then 8.5 ml epibromohydrin was added dropwise within 30 min and stirred overnight. The residue was taken up in ether after removing the solvent, washed twice with water and dried. The desired compound crystallized on evaporation of the solution. Yield 28.5 g (62%).

Aufarbeitung

  1. stirringstirred overnight
  2. customafter removing the solvent
  3. washwashed twice with water
  4. customdried
  5. customThe desired compound crystallized on evaporation of the solution

Quellen und Nachweise

ORD-Eintrag
ord-9056b7813aa146589d3b2174d64054f7
Quelldatensatz
uspto-grants-2001_01
Patentnummer
US06177469B1

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