2-Bromophenyl isocyanate → sb 225002

HRID 567977Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 567977
[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH2:4].[Br:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[N:19]=[C:20]=[O:21]>>[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH:4][C:20]([NH:19][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=1[Br:12])=[O:21]

Komponenten

3

Edukt 2

HCID 1370972-Bromophenyl isocyanateHCID 49847212-Amino-5-Nitrophenol

Produkt 1

HCID 3854666sb 225002Ausbeute 47 %

Versuchsvorschrift

N-(2-Hydroxy-4-nitrophenyl)-N′-(2-bromophenyl)urea was prepared from 2-hydroxy 4-nitro aniline (500 mg, 3.24 mmol) and 2-bromophenylisocyanate (3.24 mmol) according to the procedure in General Method B. The product was purified by dilution with methylene chloride and precipitation with hexanes. Filtering afforded the title compound(530 mg, 47%). EI-MS m/z 350(M−H)−.

Aufarbeitung

  1. customThe product was purified by dilution with methylene chloride and precipitation with hexanes
  2. filtrationFiltering

Quellen und Nachweise

ORD-Eintrag
ord-0b8d6ddc19454ca59a5a4ec5774f95f1
Quelldatensatz
uspto-grants-2001_01
Patentnummer
US06180675B2

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