m-Chloroperbenzoic acid → Methyl thieno[3,4-b]thiophene-2-carboxylate

HRID 572904Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 572904
[CH3:1][O:2][C:3]([C:5]1[S:9][C:8]2[CH2:10][S:11][CH2:12][C:7]=2[CH:6]=1)=[O:4].C1C=C(Cl)C=C(C(OO)=O)C=1>C(OCC)(=O)C.C(=O)=O>[S:9]1[C:5]([C:3]([O:2][CH3:1])=[O:4])=[CH:6][C:7]2=[CH:12][S:11][CH:10]=[C:8]12

Komponenten

5

Edukt 2

HCID 70297m-Chloroperbenzoic acidHCID 3441857Methyl 4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate

Produkt 1

HCID 19007653Methyl thieno[3,4-b]thiophene-2-carboxylate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 280Carbon DioxideLösungsmittelHCID 8857Ethyl AcetateLösungsmittel2×

Versuchsvorschrift

A solution of 2.0 g (10 mmol) (3) in 30 mL ethyl acetate was stirred and cooled down in dry ice bath. MCPBA (1.75 g, 10 mmol) in 30 mL ethyl acetate was added dropwise to the reaction solution. After the addition, the mixture was kept stirring for overnight. Then the solvent was removed by evaporation and the residue contained a crude product of (4) and 3-chlorobenzoic acid.

Aufarbeitung

  1. additionAfter the addition
  2. customThen the solvent was removed by evaporation

Quellen und Nachweise

ORD-Eintrag
ord-d05f430b1b2c4181be7bdca80667deae
Quelldatensatz
uspto-grants-2015_05
Patentnummer
US09029499B2

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