HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methylphenidate Hydrochloride → Methylphenidate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methylphenidate Hydrochloride | HCID 9280 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | Methylphenidate | HCID 4158 | — |
Reaktionsschritte
In a preferred manufacturing process, methylphenidate HCl and microcrystalline cellulose (Avicel PH-101) are blended in a Hobart Mixer. Purified water is added to the dry mixture and the wet granulation is extruded (MG-55 Multi granulator). The extrudate is then spheronized into pellets (Caleva Model# SPH250). The wet pellets are dried (Fluid Air Model#0050) and sieved (30 mesh<Acceptable<20 mesh).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09034902B2 |
| Quelldatensatz | uspto-grants-2015_05 |
| ORD ID | ord-12517afc368e49b784f3677fab99936b |
| Quellennotiz | uspto-grants-2015_05 |