HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dibenzylamine → 2-(3-(Dibenzylamino)-2-hydroxypropyl)isoindoline-1,3-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dibenzylamine | HCID 7656 | — |
| Edukt | N-(2,3-Epoxypropyl)phthalimide | HCID 21601 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 2-(3-(Dibenzylamino)-2-hydroxypropyl)isoindoline-1,3-dione | HCID 10408694 | 56,2% |
Reaktionsbedingungen
| Temperatur | 80 °C |
|---|
Reaktionsschritte
A mixture of 2-(oxiran-2-ylmethyl)isoindoline-1,3-dione (4.06 g, 20.0 mmol) and dibenzylamine (5.0 g, 25.4 mmol) was stirred at 80° C. overnight. EtOH (50 mL) was added, and stirred at room temperature. The mixture was filtered to give white solid (4.5 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09434726B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-b2a2f15a0b8848bb82600afc499c63de |
| Quellennotiz | uspto-grants-2016_09 |