HRID57595

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7656

Dibenzylamine

C14H15N

HCID21601

1H-Isoindole-1,3(2H)-dione, 2-(2-oxiranylmethyl)-

C11H9NO3

PRODUCTS

生成物

结构：O=C1c2ccccc2C(=O)N1CC(O)CN(Cc1ccccc1)Cc1ccccc1

HCID10408694

2-[3-[Bis(phenylmethyl)amino]-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione

C25H24N2O3

收率 56.2%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

CONDITIONS

反应条件

温度: 80 °C

PROCEDURE

实验过程

A mixture of 2-(oxiran-2-ylmethyl)isoindoline-1,3-dione (4.06 g, 20.0 mmol) and dibenzylamine (5.0 g, 25.4 mmol) was stirred at 80° C. overnight. EtOH (50 mL) was added, and stirred at room temperature. The mixture was filtered to give white solid (4.5 g).

WORKUP

后处理

stirringstirred at room temperature
filtrationThe mixture was filtered