Sodium Hydroxide → Benzyl(2-methylpropyl)amine

HRID 579839Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 579839
[H-].[Al+3].[Li+].[H-].[H-].[H-].[CH:7](=[N:14][CH2:15][CH:16]([CH3:18])[CH3:17])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[OH-].[Na+]>CCOCC>[CH3:17][CH:16]([CH3:18])[CH2:15][NH:14][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Komponenten

5

Edukt 3

HCID 14798Sodium HydroxideHCID 118050671-Propanamine, 2-methyl-N-(phenylmethylene)-HCID 21226445Aluminium lithium hydride

Produkt 1

HCID 211729Benzyl(2-methylpropyl)amineAusbeute 90,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

To a stirred solution of lithium aluminum hydride (23 g, 606 mmol) in ether (115 ml) was added an ethereal solution (115 ml) of N-benzylidene-2-methyl-1-propanamine (72.1 g, 447 mmol) over a period of 45 minutes. It was then refluxed for one hour. The reaction mixture was cooled in an ice bath and while stirring vigorously, aqueous sodium hydroxide (20%, 120 ml) was added dropwise. The ether solution was separated, dried over magnesium sulfate and concentrated to dryness yielding 66.1 g of the title compound.

Aufarbeitung

  1. temperatureIt was then refluxed for one hour
  2. temperatureThe reaction mixture was cooled in an ice bath
  3. customThe ether solution was separated
  4. dry with materialdried over magnesium sulfate
  5. concentrationconcentrated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-67f93610a6b642f4894926ad22ab25d9
Quelldatensatz
uspto-grants-1988_06
Patentnummer
US04749792

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