4-Nitrobenzaldehyde → p-Nitrobenzaldoxime

HRID 580083Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 580083
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.[NH2:13][OH:14].Cl>CO.O>[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[N:13][OH:14])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Komponenten

5

Edukt 2

HCID 5414-NitrobenzaldehydeHCID 22471726Hydroxylamine dihydr-ochloride

Produkt 1

HCID 96339p-NitrobenzaldoximeAusbeute 96,3 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 962WaterLösungsmittel2×

Reaktionsbedingungen

Temperatur
30 °C

Versuchsvorschrift

453 g (3 mols) of p-nitrobenzaldehyde was dissolved in 1350 ml of methanol and then, an aqueous solution of 241 g (3.3 mols) of hydrochloric acid hydroxylamine hydrochloride in 300 ml of water was added dropwise over 30 minutes while maintaining the reaction temperature at 30° C. Thereafter, stirring was effected at the same temperature for two hours and the mixture was diluted with 2000 ml of water. White crystals deposited were filtered, washed with water and dried. 480 g of p-nitrobenzaldoxime was obtained (yield, 96.5%). M.P. 128° to 131° C.

Aufarbeitung

  1. filtrationWhite crystals deposited were filtered
  2. washwashed with water
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-43e5868c1ad648ac86e21e30d1b2af03
Quelldatensatz
uspto-grants-1988_06
Patentnummer
US04751328

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