Ammonium Hydroxide → 5-Bromopyridine-2-sulfonamide
Reaktionsgleichung
Cl.[Br:2][C:3]1[CH:4]=[CH:5][C:6]([S:9](Cl)(=[O:11])=[O:10])=[N:7][CH:8]=1.[OH-].[NH4+:14]>>[Br:2][C:3]1[CH:4]=[CH:5][C:6]([S:9]([NH2:14])(=[O:11])=[O:10])=[N:7][CH:8]=1Komponenten
3
Reaktionsbedingungen
- Temperatur
- 70 °C
Versuchsvorschrift
To a 4 mL vial equipped with a magnetic stir bar were added 5-bromopyridine-2-sulfonyl chloride hydrochloride (250 mg, 0.853 mmol) and ammonium hydroxide (1329 μL, 34.1 mmol) to give a white suspension, which was heated to 70° C. in a sand bath overnight. The solvent was subsequently evaporated to give the title compound, which was used without further purification.
Aufarbeitung
- customTo a 4 mL vial equipped with a magnetic stir bar
- customto give a white suspension, which
- customThe solvent was subsequently evaporated
Quellen und Nachweise
- ORD-Eintrag
- ord-079c2d860f624468a24d1ac13482ea9b
- Quelldatensatz
- uspto-grants-2016_09
- Patentnummer
- US09434743B2
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