HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 582061Erstellt: 26. Oktober 2026
Hydrogen Bromide → (1H-benzimidazol-2-yl)(piperidin-4-yl)amine hydriodic acid
https://huagongshe.com/reaction/582061
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Hydrogen Bromide | HCID 260 | — |
| Edukt | Hydrogen iodide | HCID 24841 | — |
| Edukt | 1-Piperidinecarboxylic acid, 4-(1H-benzimidazol-2-ylamino)-, ethyl ester | HCID 3018455 | — |
| Produkt | (1H-benzimidazol-2-yl)(piperidin-4-yl)amine hydriodic acid | HCID 86754231 | — |
Reaktionsschritte
Combine (1H-benzimidazol-2-yl)(1-ethoxycarbonylpiperidin-4-yl)amine (4.63 g, 16 mmol) and 48% hydrobromic acid (75 mL). Heat to reflux. After 1.5 hours, cool and evaporate in vacuo to give a solid. Add 47% hydriodic acid (30 mL) and heat at about 90° C. After 30 minutes cool to obtain a solid. Collect the solid by filtration, rinse with ethanol and diethyl ether, and dry to give the title compound: mp; >290° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US05922737 |
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| Quelldatensatz | uspto-grants-1999_07 |
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| ORD ID | ord-aee88f53eb1d437ca8bfa1a5fbb4d85e |
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| Quellennotiz | uspto-grants-1999_07 |
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