1-Chloro-N,N-2-trimethylpropenylamine → HCID 9921388, Verbindung

HRID 584252Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 584252
[Cl:1]C(N(C)C)=C(C)C.[CH3:9][N:10]1[CH:14]=[C:13]([NH:15][C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])[CH:12]=[C:11]1[C:23]([OH:25])=O>>[CH3:9][N:10]1[CH:14]=[C:13]([NH:15][C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])[CH:12]=[C:11]1[C:23]([Cl:1])=[O:25]

Komponenten

3

Edukt 2

HCID 6407921-Chloro-N,N-2-trimethylpropenylamineHCID 27356364-[(tert-Butoxycarbonyl)amino]-1-methyl-1H-pyrrole-2-carboxylic acid

Produkt 1

HCID 9921388HCID 9921388, Verbindung

Versuchsvorschrift

N-(1-chloro-2-methylprop-1-enyl)-N,N-dimethylamine (31 μL, 0.23 mmol) was added to a mixture of 1-methyl-4-(BOC amino)pyrrole-2-carboxylic acid (50 mg, 0.21 mmol) in CDCl3 (200 mL). After a few minutes, the 1H-NMR of the reaction mixture showed complete conversion of the acid to the acid chloride. The proton spectrum of this solution of acid chloride did not change on standing overnight at room temperature. 1H NMR (CDCl3): δ 7.35 (br s, 1H), 6.93 (d, J=2 Hz, 1H), 6.46 (br s, 1H), 3.82 (s, 3H), 1.50 (s, 9H).

Aufarbeitung

  1. waitAfter a few minutes

Quellen und Nachweise

ORD-Eintrag
ord-afa3c535208a450babc46ae57d263d2a
Quelldatensatz
uspto-grants-2005_08
Patentnummer
US06924396B2

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