HCID 69084602, Verbindung → 3-(1H-1,2,3-triazol-1-yl)benzaldehyde

HRID 594252Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 594252
[N:1]1([C:6]2[CH:7]=[C:8]([CH2:12][OH:13])[CH:9]=[CH:10][CH:11]=2)[CH:5]=[CH:4][N:3]=[N:2]1>C(Cl)Cl.O=[Mn]=O>[N:1]1([C:6]2[CH:7]=[C:8]([CH:9]=[CH:10][CH:11]=2)[CH:12]=[O:13])[CH:5]=[CH:4][N:3]=[N:2]1

Komponenten

4

Edukt 1

HCID 69084602HCID 69084602, Verbindung

Produkt 1

HCID 834815293-(1H-1,2,3-triazol-1-yl)benzaldehyde

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 14801Manganese dioxideKatalysatorHCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

A solution of (3-(1H-1,2,3-triazol-1-yl)phenyl)methanol (55 mg; 0.31 mmol) in anh. DCM (1 ml) was treated with MnO2 (411 mg; 4.73 mmol), and the resulting mixture was stirred at rt, under nitrogen, for 2 h. The resulting reaction mixture was then filtered over celite, and the separated solids were washed with DCM. The filtrate was concentrated to dryness under reduced pressure giving 3-(1H-1,2,3-triazol-1-yl)benzaldehyde as a colorless solid. LC-MS (conditions A): tR=0.45 min.; [M+H]+: 174.09 g/mol.

Aufarbeitung

  1. customThe resulting reaction mixture
  2. filtrationwas then filtered over celite
  3. washthe separated solids were washed with DCM
  4. concentrationThe filtrate was concentrated to dryness under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-30590ce99abd4e7d956920c9f258784d
Quelldatensatz
uspto-grants-2016_01
Patentnummer
US09242970B2

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