4-Fluoroanilinium 2,3-dichloromaleate → Fluoroimide

HRID 596186

Reaktionsgleichung

Reaktionsgleichung von HRID 596186
[Cl:1]/[C:2](=[C:6](\[Cl:10])/[C:7]([O-])=[O:8])/[C:3]([O-])=[O:4].[F:11][C:12]1[CH:18]=[CH:17][C:15]([NH3+:16])=[CH:14][CH:13]=1.FC1C=CC([NH3+])=CC=1>O>[F:11][C:12]1[CH:18]=[CH:17][C:15]([N:16]2[C:3](=[O:4])[C:2]([Cl:1])=[C:6]([Cl:10])[C:7]2=[O:8])=[CH:14][CH:13]=1

Komponenten

3

Edukt 1

HCID 867345124-Fluoroanilinium 2,3-dichloromaleate

Produkt 1

HCID 93228FluoroimideAusbeute 95 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

5.56g of the thusly resulted 4-fluoroanilinium 2,3-dichloromaleate was suspended in 40 ml of water and allowed to react for 2 hours at reflux temperatures. Upon cooling the reaction mixture, precipitated crystal was separated by filtration to obtain 4.8g of N-(4-fluorophenyl)-2,3-dichloromaleimide melting at 240°-242° C (not corrected) at a yield of 95.0%. An analysis by gas chromatography showed the product had a purity of 99.2%.

Aufarbeitung

  1. customto react for 2 hours
  2. temperatureat reflux temperatures
  3. temperatureUpon cooling the reaction mixture
  4. customprecipitated crystal
  5. customwas separated by filtration

Quellen und Nachweise

ORD-Eintrag
ord-689ffb5d591e43528a38e99e1ae3dcb2
Quelldatensatz
uspto-grants-1977_03
Patentnummer
US04010182

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