5-[p-(1-Cyclooctenyl)-phenoxy]-pentanoic acid ethyl ester → 5-(p-Cyclooctyl-phenoxy)-pentanoic acid ethyl ester

HRID 597306

Reaktionsgleichung

Reaktionsgleichung von HRID 597306
[CH2:1]([O:3][C:4](=[O:24])[CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH:17]=2)=[CH:12][CH:11]=1)[CH3:2].[H][H]>[Pd].C(O)C>[CH2:1]([O:3][C:4](=[O:24])[CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([CH:16]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)=[CH:12][CH:11]=1)[CH3:2]

Komponenten

5

Edukt 2

HCID 543745795-[p-(1-Cyclooctenyl)-phenoxy]-pentanoic acid ethyl esterHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 543712055-(p-Cyclooctyl-phenoxy)-pentanoic acid ethyl ester

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

2 g of palladium on charcoal (5% strength) are added to a solution of 20 g of 5-[p-(1-cyclooctenyl)-phenoxy]-pentanoic acid ethyl ester in 100 ml of ethanol and hydrogenation is carried out at room temperature and normal pressure until one equivalent of hydrogen has been absorbed. The catalyst is then filtered off and the filtrate is evaporated to dryness in vacuo. Distillation of the evaporation residue in a high vacuum gives 5-(p-cyclooctyl-phenoxy)-pentanoic acid ethyl ester of boiling point 170° -175° C at 0.05 mm Hg.

Aufarbeitung

  1. customis carried out at room temperature
  2. filtrationThe catalyst is then filtered off
  3. customthe filtrate is evaporated to dryness in vacuo
  4. distillationDistillation of the evaporation residue in a high vacuum

Quellen und Nachweise

ORD-Eintrag
ord-f98040b25c974e0393e288e063af74d1
Quelldatensatz
uspto-grants-1977_03
Patentnummer
US04013708

Verknüpfte Notizen

Wird geladen…