8-(4-Methoxyphenyl)-1,4-dioxaspiro[4.5]dec-7-ene → HCID 67057737, Verbindung

HRID 604667Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 604667
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH2:18][CH2:17][C:12]3([O:16][CH2:15][CH2:14][O:13]3)[CH2:11][CH:10]=2)=[CH:5][CH:4]=1>CCO.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:18][CH2:17][C:12]3([O:16][CH2:15][CH2:14][O:13]3)[CH2:11][CH2:10]2)=[CH:5][CH:4]=1

Komponenten

4

Edukt 1

HCID 148634918-(4-Methoxyphenyl)-1,4-dioxaspiro[4.5]dec-7-ene

Produkt 1

HCID 67057737HCID 67057737, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

To a solution of 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]dec-7-ene (526.8 mg, 2.14 mmoL) in EtOH (20 mL) was added 10% Pd/C (50 mg). The reaction was put under an atmosphere of H2 (balloon) and stirred vigorously at room temperature. After 1.5 hours, the catalyst was removed by filtration. The filtrate was concentrated to afford 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane. 1H NMR (500 MHz, CDCl3): δ 7.14-7.17 (m, 2H), 6.82-6.85 (m, 2H), 3.98 (s, 4H), 3.79 (s, 3H), 2.52 (m, 1H), 1.64-1.86 (m, 8H).

Aufarbeitung

  1. customthe catalyst was removed by filtration
  2. concentrationThe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-f9e80bc20e31475ab37f48e1c6ff31e8
Quelldatensatz
uspto-grants-2011_03
Patentnummer
US07910592B2

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