3-(Trifluoromethyl)piperidine → 5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)-N-[oxido(phenyl){3-[3-(trifluoromethyl)piperidin-1-yl]propyl}--sulfanylidene]nicotinamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	3-(Trifluoromethyl)piperidine	HCID 2760776	—
Edukt	N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide	HCID 76585264	—
Produkt	5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)-N-[oxido(phenyl){3-[3-(trifluoromethyl)piperidin-1-yl]propyl}--sulfanylidene]nicotinamide	HCID 57657831	—

Reaktionsschritte

In a manner similar to that described for example 508, N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide and 3-(trifluoromethyl)piperidine were converted to the title compound.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07915443B2
Quelldatensatz	uspto-grants-2011_03
ORD ID	ord-7ca638d8ea4c4f1086a68f57dd3590a2
Quellennotiz	uspto-grants-2011_03