Acetic Acid → HCID 19595325, Verbindung
Reaktionsgleichung
[CH2:1]([C:5]1[C:14](=[O:15])[C:13]2[CH2:12][CH2:11][CH2:10][CH2:9][C:8]=2[N:7]([CH2:16][C:17]2[CH:22]=[CH:21][C:20]([C:23]3[C:24]([C:29]([O:31]C)=[O:30])=[CH:25][CH:26]=[CH:27][CH:28]=3)=[CH:19][CH:18]=2)[CH:6]=1)[CH2:2][CH2:3][CH3:4].[C:33](O)(=O)C>[OH-].[Na+]>[CH2:1]([C:5]1[C:14](=[O:15])[C:13]2[CH2:12][CH:11]([CH3:33])[CH2:10][CH2:9][C:8]=2[N:7]([CH2:16][C:17]2[CH:18]=[CH:19][C:20]([C:23]3[C:24]([C:29]([OH:31])=[O:30])=[CH:25][CH:26]=[CH:27][CH:28]=3)=[CH:21][CH:22]=2)[CH:6]=1)[CH2:2][CH2:3][CH3:4]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 60 °C
Versuchsvorschrift
Using the procedure of Example 31, 0.4 g of product A of Example 32 in 10 ml of 2N sodium hydroxide were reacted. The mixture was stirred over-night at about 60° C. and the medium was cooled to ambient temperature, acidified with glacial acetic acid, decanted, impasted in a solution of 2N hydrochloric acid, separated, dried and crystallized from 50 ml of an ethanol-water 49-1 mixture to obtain 0.220 g of the expected product melting at 255° C.