Acetic Acid → 3,4-Dimethyl-2-methylenevaleraldehyde

HRID 61326

Reaktionsgleichung

Reaktionsgleichung von HRID 61326
[CH2:1](NCCCC)CCC.C(O)(=O)C.C=O.[CH3:16][CH:17]([CH:21]([CH3:23])[CH3:22])[CH2:18][CH:19]=[O:20]>C1(C)C=CC=CC=1>[CH3:16][CH:17]([CH:21]([CH3:23])[CH3:22])[C:18](=[CH2:1])[CH:19]=[O:20]

Komponenten

6

Edukt 4

HCID 176Acetic AcidHCID 712FormaldehydeHCID 8148DibutylamineHCID 868553,4-Dimethylpentanal

Produkt 1

HCID 30204233,4-Dimethyl-2-methylenevaleraldehyde

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Reaktionsbedingungen

Temperatur
70 °C

Versuchsvorschrift

Dibutylamine (34 g), acetic acid (15.78 g), and formaldehyde (230 g) were charged to a reaction flask and heated to 70° C. 3,4-Dimethyl-pentanal (500 g) was fed over 2 hours and aged for another hour. The reaction mixture was cooled down and toluene (200 mL) was added. The reaction mixture was sequentially washed with water (2 L), sodium carbonate solution (1 L), and brine (1 L) to provide the crude product 3,4-dimethyl-2-methylene-pentanal.

Aufarbeitung

  1. waitaged for another hour
  2. temperatureThe reaction mixture was cooled down
  3. washThe reaction mixture was sequentially washed with water (2 L), sodium carbonate solution (1 L), and brine (1 L)

Quellen und Nachweise

ORD-Eintrag
ord-0e1cd97cb31d443f8b2e6efc5a30b738
Quelldatensatz
uspto-grants-2016_09
Patentnummer
US09441185B2

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