Nitric Acid → HCID 178433402, Verbindung
Reaktionsgleichung
S(=O)(=O)(O)O.[CH3:6][C:7]1[NH:8][CH:9]=[CH:10][N:11]=1.NC(N)=O.[N+:16]([O-])([OH:18])=[O:17]>O>[CH3:6][C:7]1[NH:8][CH:9]=[C:10]([N+:16]([O-:18])=[O:17])[N:11]=1Komponenten
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S(=O)(=O)(O)O.[CH3:6][C:7]1[NH:8][CH:9]=[CH:10][N:11]=1.NC(N)=O.[N+:16]([O-])([OH:18])=[O:17]>O>[CH3:6][C:7]1[NH:8][CH:9]=[C:10]([N+:16]([O-:18])=[O:17])[N:11]=1A mixture of 2,730 parts of sulfuric acid (35 percent by weight), 835 parts of 2-methylimidazole, 410 parts of urea, 2,465 parts of nitric acid (32 percent by weight) and 1,350 parts of water is reacted continuously in a three-stage cascade (consisting of 3 reactors each with a distillation column and reflux condenser) for 6 hours at from 125° to 133° C. During the reaction, 1,130 parts of 14.4 percent strength by weight nitric acid distill off. The reaction mixture is then diluted with a 3.5-fold volume of water whilst cooling and is neutralized to pH 3-4 with ammonia solution. The 2-methyl-4-nitroimidazole which separates out is centrifuged off, washed, dried and recrystallized from water. 1,060 parts of 2-methyl-4-nitroimidazole (81.5% of theory) of melting point 145°-146° C. are obtained.
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