HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → N-(Butan-2-yl)-N-methyl-1-phenylisoquinoline-3-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | Ethyl chloroformate | HCID 10928 | — |
| Edukt | N-Methyl-2-butanamine | HCID 111026 | — |
| Edukt | 1-Phenylisoquinoline-3-carboxylic acid | HCID 407896 | — |
| Lösungsmittel | Chloroform | HCID 6212 | — |
| Produkt | N-(Butan-2-yl)-N-methyl-1-phenylisoquinoline-3-carboxamide | HCID 13272363 | 63,5% |
Reaktionsschritte
Operations are carried out as for Example 7, starting with 2.96 g of 1-phenyl isoquinoline 3-carboxylic acid, 1.33 g of triethylamine, 1.49 g of ethyl chloroformate and 1.34 g of N-methyl 2-butanamine in 120 ml of chloroform. 2.4 g of N-methyl N(1-methyl propyl) 1-phenyl isoquinoline 3-carboxamide melting at 95°-96° C., are obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04499094 |
| Quelldatensatz | uspto-grants-1985_02 |
| ORD ID | ord-b729fd781ac7454fb621227a888506ed |
| Quellennotiz | uspto-grants-1985_02 |