HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dibutylamine → N,N-dibutyl 1-phenyl isoquinoline 3-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dibutylamine | HCID 8148 | — |
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | Ethyl chloroformate | HCID 10928 | — |
| Edukt | 1-Phenylisoquinoline-3-carboxylic acid | HCID 407896 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | N,N-dibutyl 1-phenyl isoquinoline 3-carboxamide | HCID 20427637 | 41,5% |
Reaktionsschritte
Operations are carried out as for Example 7, starting from 2.5 g of 1-phenyl isoquinoline 3-carboxylic acid, 1.15 g of triethylamine, 1.24 g of ethyl chloroformate and 1.66 g of dibutylamine in 100 ml of toluene. After chromatography and recrystallization in petroleum ether, 1.5 g of N,N-dibutyl 1-phenyl isoquinoline 3-carboxamide melting at 62° C. is obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04499094 |
| Quelldatensatz | uspto-grants-1985_02 |
| ORD ID | ord-f1d271207d2244c4886c1a155473a2b5 |
| Quellennotiz | uspto-grants-1985_02 |