3-Amino-1,2-propanediol → HCID 21844884, Verbindung
Reaktionsgleichung
[N+:1]([C:4]1[CH:5]=[C:6]([NH:14][C:15]([C:17]2[CH:22]=[C:21]([C:23](OC)=[O:24])[CH:20]=[C:19]([N+:27]([O-:29])=[O:28])[CH:18]=2)=[O:16])[CH:7]=[C:8]([C:10](OC)=[O:11])[CH:9]=1)([O-:3])=[O:2].[NH2:30][CH2:31][CH:32]([OH:35])[CH2:33][OH:34]>>[N+:1]([C:4]1[CH:5]=[C:6]([NH:14][C:15]([C:17]2[CH:22]=[C:21]([C:23]([NH:30][CH2:31][CH:32]([OH:35])[CH2:33][OH:34])=[O:24])[CH:20]=[C:19]([N+:27]([O-:29])=[O:28])[CH:18]=2)=[O:16])[CH:7]=[C:8]([C:10]([NH:30][CH2:31][CH:32]([OH:35])[CH2:33][OH:34])=[O:11])[CH:9]=1)([O-:3])=[O:2]Komponenten
3
Reaktionsbedingungen
- Temperatur
- 90 °C
Versuchsvorschrift
3-Nitro-5-methoxycarbonylphenylaminocarbonyl-(3'-nitro-5'-methoxycarbonylbenzene) (1.21 g, 3.0 mmol) was suspended in aminopropan-2,3-diol (0.55 g, 6.0 mmol) and the mixture was heated to 90° C. After 30 min, the pressure was reduced to 200 mm Hg and heating was continued for 90 min. The product was purified by preparative HPLC. Yield: 0.73 g (47%).
Aufarbeitung
- temperatureheating
- wait