p-Toluenesulfonic acid → 2-(Chloroethyl)-3-methyl-5,6-dihydro-1,4-dithiin

HRID 620807

Reaktionsgleichung

Reaktionsgleichung von HRID 620807
Cl[CH:2]([CH2:6][CH2:7][Cl:8])[C:3](=O)[CH3:4].[CH:9]([SH:12])(S)[CH3:10].CC1C=CC([S:20](O)(=O)=O)=CC=1>C1(C)C=CC=CC=1>[Cl:8][CH2:7][CH2:6][C:2]1[S:20][CH2:10][CH2:9][S:12][C:3]=1[CH3:4]

Komponenten

5

Edukt 3

HCID 6101p-Toluenesulfonic acidHCID 336451,1-EthanedithiolHCID 940323,5-Dichloropentan-2-one

Produkt 1

HCID 145517102-(Chloroethyl)-3-methyl-5,6-dihydro-1,4-dithiinAusbeute 32 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

A mixture of 0.1 mole (15.4 g.) 3,5-dichloro-2-pentanone, 0.1 mole (9.4 g.) ethanedithiol and 0.3 mole PTSA was stirred at room temperature overnight. The product was taken up in toluene, washed with 5% sodium bicarbonate and water, dried over magnesium sulfate, filtered and the solvent removed. The product was distilled; bp. 114°-116°/0.7 mm. Yield 32%.

Aufarbeitung

  1. washwashed with 5% sodium bicarbonate and water
  2. dry with materialdried over magnesium sulfate
  3. filtrationfiltered
  4. customthe solvent removed
  5. distillationThe product was distilled

Quellen und Nachweise

ORD-Eintrag
ord-6f50d090d94348cfbe37538b26c65891
Quelldatensatz
uspto-grants-1989_04
Patentnummer
US04822813

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