Hydrochloric Acid → 1-(Oxan-4-yl)piperazine--hydrogen chloride (1/2)

HRID 624415Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 624415
[O:1]1[CH2:6][CH2:5][CH:4]([N:7]2[CH2:12][CH2:11][N:10](C(OC(C)(C)C)=O)[CH2:9][CH2:8]2)[CH2:3][CH2:2]1.[ClH:20]>CCOCC>[ClH:20].[ClH:20].[O:1]1[CH2:6][CH2:5][CH:4]([N:7]2[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)[CH2:3][CH2:2]1

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 46785855HCID 46785855, Verbindung

Produkt 1

HCID 441204811-(Oxan-4-yl)piperazine--hydrogen chloride (1/2)

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

To a solution of EXAMPLE 336A (3.92 g) in ether was added HCl (25 mL, 2M in ether) and the reaction mixture was stirred for 16 hours at room temperature. The solid product was filtered off, dried and used in next step without further purification.

Aufarbeitung

  1. filtrationThe solid product was filtered off
  2. customdried
  3. customused in next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-138b7f02e2b34323a9cfec14d6691810
Quelldatensatz
uspto-grants-2016_04
Patentnummer
US09303025B2

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