3,4-dihydro-2H-pyran → 2H-Pyran, 2-[(12-bromododecyl)oxy]tetrahydro-

HRID 635790Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 635790
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][OH:14].C1(C)C=CC(S([O-])(=O)=O)=CC=1.[NH+]1C=CC=CC=1.[O:32]1[CH:37]=[CH:36][CH2:35][CH2:34][CH2:33]1>ClCCl>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][O:14][CH:33]1[CH2:34][CH2:35][CH2:36][CH2:37][O:32]1

Komponenten

5

Edukt 3

HCID 80803,4-dihydro-2H-pyranHCID 13789512-Bromo-1-dodecanolHCID 466102Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1)

Produkt 1

HCID 110785922H-Pyran, 2-[(12-bromododecyl)oxy]tetrahydro-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a solution of 12-bromo-1-dodecanol (1 mole) in dichloromethane containing pyridinium p-toluenesulfonate (P-TSA) is added dihydropyran (2 moles). The reaction mixture is stirred for 24 hours and then washed twice with water and dried over anhydrous MgSO4. The dichloromethane is removed under reduced pressure. If necessary the resulting product is purified by chromatography on silica gel.

Aufarbeitung

  1. washwashed twice with water
  2. dry with materialdried over anhydrous MgSO4
  3. customThe dichloromethane is removed under reduced pressure
  4. customIf necessary the resulting product is purified by chromatography on silica gel

Quellen und Nachweise

ORD-Eintrag
ord-4d804cb2e89a4d62a903166886d19112
Quelldatensatz
uspto-grants-2001_02
Patentnummer
US06191105B1

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