Sodium Acetate → 2-(1,3-Dioxolan-2-yl)-4-methoxyaniline

HRID 639352Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 639352
[O:1]1[CH2:5][CH2:4][O:3][CH:2]1[C:6]1[CH:11]=[C:10]([O:12][CH3:13])[CH:9]=[CH:8][C:7]=1[N+:14]([O-])=O.C([O-])(=O)C.[Na+]>C(OCC)(=O)C.[Pt]=O>[O:1]1[CH2:5][CH2:4][O:3][CH:2]1[C:6]1[CH:11]=[C:10]([O:12][CH3:13])[CH:9]=[CH:8][C:7]=1[NH2:14]

Komponenten

5

Edukt 2

HCID 517045Sodium AcetateHCID 572490272-(5-Methoxy-2-nitrophenyl)-1,3-dioxolane

Produkt 1

HCID 153389082-(1,3-Dioxolan-2-yl)-4-methoxyaniline

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 82844Platinum oxide (PtO)KatalysatorHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

A solution of 2-(1,3-dioxolan-2-yl)-4-methoxy-1-nitrobenzene (1eq) in ethyl acetate was treated with sodium acetate (0.08eq) and platinum oxide (0.06eq) and hydrogenated in a Parr apparatus at 50 psi for 16 hours. The reaction mixture was filtered and the filtrate was concentrated to give 2-(1,3-dioxolan-2yl)-4-methoxyphenylamine in quantitative yield.

Aufarbeitung

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-4acf5e206270489eb1fa7a8ca652d9a3
Quelldatensatz
uspto-grants-2010_04
Patentnummer
US07691866B2

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