ethyl 2-methyl-1H-indole-3-carboxylate → 2-Methyl-1-phenyl-1H-indole-3-carboxylic acid ethyl ester
Reaktionsgleichung
[CH2:1]([O:3][C:4]([C:6]1[CH:10]=[CH:9][N:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:7]=1[CH3:17])=[O:5])[CH3:2].C(O[C:21]([C:23]1C2C(=CC=CC=2)N[C:24]=1[CH3:32])=O)C>>[CH2:1]([O:3][C:4]([C:6]1[C:10]2[C:9](=[CH:21][CH:23]=[CH:24][CH:32]=2)[N:8]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:7]=1[CH3:17])=[O:5])[CH3:2]Komponenten
3
Versuchsvorschrift
Prepared in analogy to that of 2-methyl-1-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester from 2-Methyl-1H-indole-3-carboxylic acid ethyl ester. The title compound, 1H NMR (200 MHz, CDCl3): δ (ppm)=8.15 (d, 1H, J=7.4 Hz), 7.6-6.9 (m, 8H), 4.43 (q, 2H, J=7.4 Hz), 2.59 (s, 3H), 1.47 (t, 3H, J=7.4 Hz).
Quellen und Nachweise
- ORD-Eintrag
- ord-077312ff0a8743a7abee8be20c68df7b
- Quelldatensatz
- uspto-grants-2010_04