Potassium Carbonate → 4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidine-1-carboxylic Acid [(R)-2-[4-(4-methyl-piperazin-1-yl)-piperidin-1-yl]-2-oxo-1-(5,6,7,8-tetrahydro-naphthalen-2-ylmethyl)-ethyl]-amide

Reaktionsgleichung

[O:1]=[C:2]1[N:8]([CH:9]2[CH2:14][CH2:13][N:12]([C:15]([NH:17][C@H:18]([CH2:22][C:23]3[CH:32]=[CH:31][C:30]4[CH2:29][CH2:28][CH2:27][CH2:26][C:25]=4[CH:24]=3)[C:19](O)=[O:20])=[O:16])[CH2:11][CH2:10]2)[CH2:7][CH2:6][C:5]2[CH:33]=[CH:34][CH:35]=[CH:36][C:4]=2[NH:3]1.CN(C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.[B-](F)(F)(F)F.C(N(C(C)C)C(C)C)C.[CH3:68][N:69]1[CH2:74][CH2:73][N:72]([CH:75]2[CH2:80][CH2:79][NH:78][CH2:77][CH2:76]2)[CH2:71][CH2:70]1.C([O-])([O-])=O.[K+].[K+]>C1COCC1>[CH3:68][N:69]1[CH2:74][CH2:73][N:72]([CH:75]2[CH2:80][CH2:79][N:78]([C:19](=[O:20])[C@H:18]([NH:17][C:15]([N:12]3[CH2:11][CH2:10][CH:9]([N:8]4[CH2:7][CH2:6][C:5]5[CH:33]=[CH:34][CH:35]=[CH:36][C:4]=5[NH:3][C:2]4=[O:1])[CH2:14][CH2:13]3)=[O:16])[CH2:22][C:23]3[CH:32]=[CH:31][C:30]4[CH2:29][CH2:28][CH2:27][CH2:26][C:25]=4[CH:24]=3)[CH2:77][CH2:76]2)[CH2:71][CH2:70]1