Chlorine → 2-Chloro-4-(trifluoromethoxy)phenol

HRID 64649

Reaktionsgleichung

Reaktionsgleichung von HRID 64649
[Cl:1]Cl.[F:3][C:4]([F:14])([F:13])[O:5][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1>C(Cl)(Cl)(Cl)Cl>[Cl:1][C:8]1[CH:7]=[C:6]([O:5][C:4]([F:13])([F:14])[F:3])[CH:11]=[CH:10][C:9]=1[OH:12]

Komponenten

4

Edukt 2

HCID 24526Chlorine2×HCID 70015p-(Trifluoromethoxy)phenol

Produkt 1

HCID 130447832-Chloro-4-(trifluoromethoxy)phenol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 5943Carbon TetrachlorideLösungsmittel

Versuchsvorschrift

Gaseous chlorine was slowly introduced to a stirred solution of 35.6 g of 4-trifluoromethoxyphenol in 100 ml carbon tetrachloride. The reaction temperature was kept at 20° to 30° C. by outer cooling. After saturaring with chlorine, the reaction mixture was stirred at 20° to 30° C. for 1 hour, cooled, washed with water, dried over anhydrous sodium sulfate, and evaporated to give a pale yellow residue. The residue was distilled under reduced pressure to give 29.8 g of 2-chloro-4-trifluoromethoxyphenol which boiled at 67°-70° C./18 mmHg.

Aufarbeitung

  1. customwas kept at 20° to 30° C. by outer cooling
  2. temperaturecooled
  3. washwashed with water
  4. dry with materialdried over anhydrous sodium sulfate
  5. customevaporated
  6. customto give a pale yellow residue
  7. distillationThe residue was distilled under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-e29a4776f309479c9773dc81cfc33bef
Quelldatensatz
uspto-grants-1986_09
Patentnummer
US04609669

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