Veratrole → 4-(3,4-Dimethoxybenzoyl)-5-ethyl-2-imidazolidinone

HRID 647832Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 647832
[CH2:1]([CH:3]1[CH:7]([C:8]([OH:10])=O)[NH:6][C:5](=[O:11])[NH:4]1)[CH3:2].[CH3:12][O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[O:20][CH3:21]>>[CH3:12][O:13][C:14]1[CH:19]=[C:18]([CH:17]=[CH:16][C:15]=1[O:20][CH3:21])[C:8]([CH:7]1[CH:3]([CH2:1][CH3:2])[NH:4][C:5](=[O:11])[NH:6]1)=[O:10]

Komponenten

3

Edukt 2

HCID 7043VeratroleHCID 13245335HCID 13245335, Verbindung

Produkt 1

HCID 132453364-(3,4-Dimethoxybenzoyl)-5-ethyl-2-imidazolidinone

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

In 100 g PPA are suspended 15.8 g 4-ethyl-2-oxoimidazolidine-5-carboxylic acid and 13.8 g 1,2-dimethoxybenzene. The mixture is rapidly stirred and heated for 5 hours at 100° C. The reaction mixture is quenched with water and the product separates as a solid. The solid is collected and washed with water and dried. Purification is effected by chromatography over silica gel.

Aufarbeitung

  1. customThe reaction mixture is quenched with water
  2. customThe solid is collected
  3. washwashed with water
  4. customdried
  5. customPurification

Quellen und Nachweise

ORD-Eintrag
ord-fa1bad0c5c654454b1385555b3940788
Quelldatensatz
uspto-grants-1983_10
Patentnummer
US04410540

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