Water → 2-Nitro-6-piperidinobenzonitrile

HRID 64860

Reaktionsgleichung

Reaktionsgleichung von HRID 64860
[N+:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-:14])=[O:13])[C:5]=1[C:6]#[N:7])([O-])=O.N1[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1.O>CN(C)C=O>[N+:12]([C:8]1[CH:9]=[CH:10][CH:11]=[C:4]([N:1]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)[C:5]=1[C:6]#[N:7])([O-:14])=[O:13]

Komponenten

5

Edukt 3

HCID 962WaterHCID 8082PiperidineHCID 520718Dinitrobenzonitrile

Produkt 1

HCID 127157822-Nitro-6-piperidinobenzonitrile

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Reaktionsbedingungen

Temperatur
50 °C

Versuchsvorschrift

5.8 g of 2,6-dinitrobenzonitrile was dissolved in 30 ml of dimethylformamide, and 10.2 ml of piperidine was added to the solution. The mixture was stirred at 50° C. for 30 minutes while externally cooling because of heat generation. The reaction mixture was poured into water, and the precipitate thus formed was collected, washed with water and then with methanol, and dried to obtain 6.7 of 2-nitro-6-piperidinobenzonitrile (melting point: 122°-123° C.).

Aufarbeitung

  1. temperaturewhile externally cooling because of heat generation
  2. customthe precipitate thus formed
  3. customwas collected
  4. washwashed with water
  5. dry with materialwith methanol, and dried

Quellen und Nachweise

ORD-Eintrag
ord-8573d96496554b0985a0d4bbbd31d42b
Quelldatensatz
uspto-grants-1986_09
Patentnummer
US04610987

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